
Research Peptide
Semax Research Peptide
Lyophilised Semax heptapeptide supplied for laboratory research.
CAS 80714-61-0 · LOT TM-2480 · HPLC ≥ 99.5%
§ Amount
§ Price
IN STOCK
§ About Semax
Semax is a synthetic seven-amino-acid peptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). It is derived from the ACTH(4-7) peptide sequence with a C-terminal Pro-Gly-Pro extension and has been investigated in laboratory and preclinical neurobiology research.
Experimental studies have examined Semax in areas including neurotrophin signalling, BDNF and NGF expression, gene-expression responses and neurological research models. Much of the mechanistic evidence comes from cellular and animal studies, so these findings should not be interpreted as established therapeutic or cognitive effects in humans. PepDirect supplies Semax exclusively for laboratory research use.
§ Scientific Specifications
- Compound Name
- Semax
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- Sequence Abbreviation
- MEHFPGP
- CAS Number
- 80714-61-0
- Molecular Formula
- C37H51N9O10S
- Molecular Weight
- 813.92 g/mol
- PubChem CID
- 9811102
- Purity
- 99%+ (HPLC verified per lot)
- Form
- Lyophilised powder
- Storage
- Store dry, 2°C to 8°C
§ Preclinical & Laboratory Research Context
- BDNF and NGF neurotrophin-expression research
- Neurotrophin-receptor and gene-expression studies
- Cellular and animal neurological research models
- Experimental signalling-pathway research
§ Quality & Batch Testing
Each batch of Semax is independently tested before it ships. Purity is verified by HPLC (High-Performance Liquid Chromatography) at ≥ 99.5%, and the current lot displayed on this product page (LOT TM-2480) corresponds to the certificate of analysis available under the Lab certificates accordion on this page.
Lot-specific COA documentation is published here before purchase and ships in the box. To confirm a lot after delivery, visit Verify your product.
§ Research References
- Semax · PubChem CID 9811102 (heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro)PubChem (NCBI)
- Semax, an ACTH(4-10) analogue, induces BDNF and trkB mRNA in the rat basal forebrain (animal study)PubMed · Dolotov et al.
- Neurotrophin (BDNF/NGF) expression research in rat glial cultures (cellular study)PubMed · Shadrina et al.
- Peptide preparation Semax attenuates experimental brain ischaemia (rodent model)PubMed · Ashmarin, Nezavibatko et al.
- Semax and its C-terminal tripeptide PGP, genome-wide expression research (cellular/animal)PubMed · Medvedeva et al.
§ FAQ
- What is Semax?
- Semax is a synthetic seven-amino-acid peptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It is derived from an ACTH peptide sequence and has been investigated in laboratory, cellular and preclinical neurobiology research.
- Is Semax a peptide?
- Yes. Semax is a heptapeptide, meaning it contains seven amino-acid residues. Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP).
- What areas of Semax research have been investigated?
- Experimental research has examined Semax in areas including BDNF and NGF expression, neurotrophin signalling, gene-expression responses and neurological model systems. Much of the mechanistic literature is based on cellular and animal research.
- How is PepDirect Semax tested?
- Semax is tested by HPLC to a purity of ≥ 99.5%. The current lot displayed on this page is TM-2480. A lot-specific Certificate of Analysis is published on the product page before purchase and ships in the box.
- Is this intended for human use?
- No. All PepDirect products are sold strictly for laboratory and research use only, and are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
- How quickly does PepDirect ship?
- Orders placed before 3:00 PM GMT are dispatched the same business day. Orders placed after 3:00 PM GMT are dispatched the next business day, with tracked delivery in 1-2 business days across the UK and EU. Shipping is calculated and shown at checkout based on destination.
- Does PepDirect provide a Certificate of Analysis?
- Yes. Every lot's COA is published on the product page before it ships, and the same PDF is included in the box.
- What is your guarantee?
- Same-day replacement on damaged or lost shipments, or a full refund on request, no questions asked.
§ Intended Use
This product is intended strictly for laboratory research applications by qualified personnel. It is not approved for human or animal consumption, and must not be used in foods, drugs, supplements, cosmetics, or diagnostics.
§ Legal Disclaimer
This compound and the statements on this page have not been evaluated by any regulatory body. No claims are made regarding diagnosis, treatment, mitigation, or prevention of any disease. Use is restricted to qualified researchers operating in appropriate laboratory environments.
§ Terms of Sale
By purchasing this product, the buyer confirms they are a qualified researcher or institutional purchaser, and accepts full responsibility for its handling, storage, and lawful use.
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Laboratory preparation supplies
Raw vial research material requires appropriate laboratory preparation equipment. The available kit groups compatible preparation and handling supplies in one bundle.
- Bacteriostatic Water 10mL
- Mixing Syringe + Needle 3mL, 23G · 10-pack
- Insulin Syringes 30G × 8mm 1mL · 10-pack
- Alcohol Prep Wipes 100-pack

§ Often bought together
Pair it with.

Accessories
Mixing Needle — 23G
23G reconstitution needle — for drawing BAC water through the vial stopper.
- IN STOCK
- COA VERIFIED

Accessories
Insulin Syringes — 30G x 8mm · 1mL
30G × 8mm insulin syringes, 1mL barrel — for Raw Vial reconstitution & injection.
- IN STOCK
- COA VERIFIED

Accessories
Alcohol Prep Wipes — 70% Isopropyl
Individually wrapped 70% isopropyl alcohol pads — 100 per pack.
- IN STOCK
- COA VERIFIED

Accessories
Sharps Disposal Bin — 0.2L
Puncture-resistant container for safe disposal of used needles and syringes.
- IN STOCK
- COA VERIFIED
