Metabolic

Retatrutide 40mg Pen Kit

Name: Retatrutide 40mg Pen Kit
Brand: PepDirect
SKU: retatrutide-pen
Price: 149.99 GBP
Availability: InStock

Pre-filled triple-agonist research pen. Supplied pre-reconstituted for laboratory research use.

Also available as: Retatrutide Raw Vial

CAS 2381089-83-2 · LOT TM-2465 · HPLC ≥ 99.5%

§ One kit

$204.61

IN STOCK

Add Travel Case + Cooler Pack+ $27.27Maintains 2–8°C cold chain during transit, pen + refill capacity.○ NOT ADDED

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§ About the Retatrutide 40mg Pen Kit

Retatrutide (research designation LY3437943) is a 39-amino-acid engineered peptide investigated in laboratory research as a simultaneous agonist of the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon receptor (GCGR). This triple-receptor profile is what published research literature refers to when it describes retatrutide as a "triple agonist".

The PepDirect Pen Kit format supplies retatrutide pre-reconstituted and pre-loaded into a dial-a-dose research pen. Compared with the Raw Vial format, this removes the sourcing, calculation, and reconstitution steps required to prepare a research solution from lyophilised powder. Which format a laboratory chooses is a workflow decision, not a dosing recommendation.

§ The three receptors, GLP-1R, GIPR, GCGR

Retatrutide is investigated in laboratory research as a simultaneous agonist of three receptors from the metabolic-hormone / incretin signalling family: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR). This triple-receptor profile is what published research literature refers to when it describes retatrutide as a "triple agonist".

§ Pen format

Pre-filled

Retatrutide is supplied pre-reconstituted in a research pen rather than as lyophilised raw powder.

Dial-controlled

Mechanical dial system for controlled laboratory dispensing.

Compatible hardware

Designed for the compatible Pen Kit hardware and consumables listed by PepDirect.

Cold storage

Follow the verified storage conditions displayed in the product specifications.

§ Scientific Specifications

Compound Name: Retatrutide (LY3437943)
CAS Number: 2381089-83-2
Molecular Formula: C221H342N46O68
Molecular Weight: 4731.33 g/mol
Amino Acid Count: 39-residue engineered peptide
Purity: 99%+ (HPLC verified per lot)
Form: Pre-filled dial-a-dose research pen (reconstituted solution), 40mg
Storage: Refrigerate 2°C to 8°C, protect from light

§ Preclinical & Laboratory Research Context

Triple GLP-1R / GIPR / GCGR receptor agonism research
Comparative research against dual GLP-1R/GIPR agonists
Incretin-pathway signalling studies in cellular and preclinical models
Energy-expenditure and glucose-regulation research readouts

§ Quality & Batch Testing

Each batch of Retatrutide Pen Kit is independently tested before it ships. Purity is verified by HPLC (High-Performance Liquid Chromatography) at ≥ 99.5%, and the current lot displayed on this product page (LOT TM-2465) corresponds to the certificate of analysis available under the Lab certificates accordion on this page.

Lot-specific COA documentation is published here before purchase and ships in the box. To confirm a lot after delivery, visit Verify your product.

§ Research References

Retatrutide (LY3437943), Triple hormone-receptor agonist research overviewPubMed · Rosenstock et al.
Pharmacological characterisation of LY3437943, a novel triple GLP-1, GIP and glucagon receptor agonistPubMed · Coskun et al.
GLP-1, GIP and glucagon receptors, incretin and metabolic signalling reviewPubMed · Müller et al.

§ FAQ

What is the Retatrutide 40mg Pen Kit?: The Retatrutide 40mg Pen Kit is a pre-filled research format containing 40mg of retatrutide in a dial-a-dose pen. It ships as a prepared solution rather than a lyophilised powder, so no reconstitution step is required in the laboratory workflow.
How does the Pen Kit differ from the Retatrutide Raw Vial?: The Raw Vial supplies retatrutide as a lyophilised (freeze-dried) powder in a sealed vial and requires reconstitution before use. The Pen Kit supplies retatrutide pre-reconstituted and pre-loaded into a research pen, removing the sourcing, calculation and reconstitution steps of the Raw Vial format. Both are supplied by PepDirect exclusively for laboratory research use.
What is retatrutide studied for in research?: Laboratory and preclinical research has examined retatrutide as a triple agonist of the GLP-1, GIP and glucagon receptors, with reported research contexts including incretin-pathway signalling, energy-expenditure readouts, and glucose-regulation pathways in cellular and animal models.
How does retatrutide differ from tirzepatide and semaglutide as research peptides?: Semaglutide is investigated as a single GLP-1 receptor agonist. Tirzepatide is investigated as a dual GLP-1R / GIPR agonist. Retatrutide adds a third target, the glucagon receptor (GCGR), giving it a triple-receptor profile in laboratory research.
Is the Retatrutide Pen Kit sold by PepDirect for human use?: No. PepDirect supplies the Retatrutide Pen Kit exclusively for laboratory research. It is not marketed as a medicine, food supplement, cosmetic or product for human or veterinary use.
How is PepDirect Retatrutide Pen Kit tested?: Retatrutide Pen Kit is tested by HPLC to a purity of ≥ 99.5%. The current lot displayed on this page is TM-2465. A lot-specific Certificate of Analysis is published on the product page before purchase and ships in the box.
Is this intended for human use?: No. All PepDirect products are sold strictly for laboratory and research use only, and are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
How quickly does PepDirect ship?: Orders placed before 3:00 PM GMT are dispatched the same business day. Orders placed after 3:00 PM GMT are dispatched the next business day, with tracked delivery in 1-2 business days across the UK and EU. Shipping is calculated and shown at checkout based on destination.
Does PepDirect provide a Certificate of Analysis?: Yes. Every lot's COA is published on the product page before it ships, and the same PDF is included in the box.
What is your guarantee?: Same-day replacement on damaged or lost shipments, or a full refund on request, no questions asked.

§ Intended Use

This product is intended strictly for laboratory research applications by qualified personnel. It is not approved for human or animal consumption, and must not be used in foods, drugs, supplements, cosmetics, or diagnostics.

§ Related Research Compounds

Learn: What is Retatrutide? →

§ Legal Disclaimer

This compound and the statements on this page have not been evaluated by any regulatory body. No claims are made regarding diagnosis, treatment, mitigation, or prevention of any disease. Use is restricted to qualified researchers operating in appropriate laboratory environments.

§ Terms of Sale

By purchasing this product, the buyer confirms they are a qualified researcher or institutional purchaser, and accepts full responsibility for its handling, storage, and lawful use.

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