Mitochondrial Peptide

MOTS-C Research Peptide

Name: MOTS-C Raw Vial
Brand: PepDirect
SKU: mots-c
Availability: InStock

Lyophilised MOTS-C mitochondrial-derived peptide supplied for laboratory research.

CAS 1627580-64-6 · LOT TM-2415 · HPLC ≥ 99.5%

§ Amount

§ Price

$40.91

IN STOCK

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§ About MOTS-C

MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded within a short open reading frame associated with mitochondrial 12S rRNA. Published laboratory research has investigated its role in mitochondria-to-nucleus signalling, and metabolic stress has been reported to influence its cellular localisation in experimental systems.

The evidence base spans cellular, animal/preclinical and some human research contexts, which should not be conflated. PepDirect supplies MOTS-C exclusively for laboratory research use.

§ Scientific Specifications

Compound Name: MOTS-C (mitochondrial ORF of the 12S rRNA-c)
CAS Number: 1627580-64-6
Molecular Formula: C101H152N28O22S2
Molecular Weight: 2174.6 g/mol
PubChem CID: 146675088
Sequence: MRWQEMGYIFYPRKLR (16 amino acids)
Purity: 99%+ (HPLC verified per lot)
Form: Lyophilised powder
Storage: Store dry, 2°C to 8°C

§ MOTS-C Research Context

Mitochondrial-to-nuclear signalling research
Metabolic-stress response experimental models
AMPK-associated signalling research
Nuclear translocation studies in experimental systems
Antioxidant-response-element / NRF2-related research
Mitonuclear communication research
Cellular energy-homeostasis research

§ Quality & Batch Testing

Each batch of MOTS-C is independently tested before it ships. Purity is verified by HPLC (High-Performance Liquid Chromatography) at ≥ 99.5%, and the current lot displayed on this product page (LOT TM-2415) corresponds to the certificate of analysis available under the Lab certificates accordion on this page.

Lot-specific COA documentation is published here before purchase and ships in the box. To confirm a lot after delivery, visit Verify your product.

§ Research References

MOTS-c · PubChem CID 146675088 (16-aa mitochondrial-derived peptide)PubChem (NCBI)
MOTS-c is an exercise-induced mitochondrial-encoded regulatory peptide (nuclear translocation)PubMed · Reynolds et al. (Cell Metabolism)
Mitochondrial-derived peptides in metabolism and ageing, reviewPubMed · Kim et al.

§ FAQ

What is MOTS-C?: MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded within a short open reading frame associated with the mitochondrial 12S rRNA. It is studied in mitochondrial biology research.
What does MOTS-C stand for?: Mitochondrial Open Reading frame of the Twelve S rRNA type-C, a peptide encoded by a small ORF within the 12S rRNA region of the mitochondrial genome.
Where is MOTS-C encoded?: In an open reading frame associated with the mitochondrial 12S rRNA, rather than in the nuclear genome, hence its description as a mitochondrial-derived peptide.
How many amino acids are in MOTS-C?: 16 amino acids (sequence MRWQEMGYIFYPRKLR).
Why is MOTS-C studied in mitochondrial research?: Published research examines its role in mitochondria-to-nucleus signalling, metabolic-stress response and cellular energy-homeostasis pathways in experimental systems.
What does the current evidence for MOTS-C consist of?: The evidence base includes cellular studies, animal/preclinical models and some human research, and these categories should not be conflated when interpreting findings.
How is PepDirect MOTS-C tested?: Every lot is supplied with lot-specific documentation. HPLC purity is reported on the product hero and full identity information is captured in the lot Certificate of Analysis.
Is this intended for human use?: No. PepDirect supplies MOTS-C as a laboratory research product only. It is not marketed as a medicine, food supplement or product for human or veterinary use.
What amounts of MOTS-C does PepDirect supply?: PepDirect currently supplies MOTS-C in the following amounts: 10mg and 20mg and 40mg. The active selection on this page controls price and stock.
How is PepDirect MOTS-C tested?: MOTS-C is tested by HPLC to a purity of ≥ 99.5%. The current lot displayed on this page is TM-2415. A lot-specific Certificate of Analysis is published on the product page before purchase and ships in the box.
Is this intended for human use?: No. All PepDirect products are sold strictly for laboratory and research use only, and are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
How quickly does PepDirect ship?: Orders placed before 3:00 PM GMT are dispatched the same business day. Orders placed after 3:00 PM GMT are dispatched the next business day, with tracked delivery in 1-2 business days across the UK and EU. Shipping is calculated and shown at checkout based on destination.
Does PepDirect provide a Certificate of Analysis?: Yes. Every lot's COA is published on the product page before it ships, and the same PDF is included in the box.
What is your guarantee?: Same-day replacement on damaged or lost shipments, or a full refund on request, no questions asked.

§ Intended Use

This product is intended strictly for laboratory research applications by qualified personnel. It is not approved for human or animal consumption, and must not be used in foods, drugs, supplements, cosmetics, or diagnostics.

§ Related Research Compounds

§ Legal Disclaimer

This compound and the statements on this page have not been evaluated by any regulatory body. No claims are made regarding diagnosis, treatment, mitigation, or prevention of any disease. Use is restricted to qualified researchers operating in appropriate laboratory environments.

§ Terms of Sale

By purchasing this product, the buyer confirms they are a qualified researcher or institutional purchaser, and accepts full responsibility for its handling, storage, and lawful use.

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Laboratory preparation supplies

Raw vial research material requires appropriate laboratory preparation equipment. The available kit groups compatible preparation and handling supplies in one bundle.