
Melanocortin Peptide
Melanotan I (Melanotan 1) Research Peptide
Lyophilised Melanotan I melanocortin peptide supplied for laboratory research.
CAS 75921-69-6 · LOT TM-2466 · HPLC ≥ 99.5%
§ Amount
§ Price
IN STOCK
§ About Melanotan I
Melanotan I is a synthetic linear alpha-MSH analogue, commonly identified in chemical databases as afamelanotide / NDP-alpha-MSH. It has been investigated in melanocortin-receptor research, including MC1R-focused structure-activity work and melanogenesis-related laboratory research.
Afamelanotide is also the established nonproprietary name associated with a licensed medicinal product in some jurisdictions. PepDirect's research material is supplied strictly as laboratory research material and is not represented as the licensed medicinal product.
§ Melanotan I and Melanotan II
Melanotan I and Melanotan II are distinct peptide identities with different structures and receptor profiles. Melanotan I is a linear alpha-MSH analogue; Melanotan II is a cyclic peptide with broader melanocortin-receptor activity. Research findings for one should not automatically be assigned to the other.
§ Scientific Specifications
- Compound Name
- Melanotan I / afamelanotide / NDP-alpha-MSH
- CAS Number
- 75921-69-6
- Molecular Formula
- C78H111N21O19
- Molecular Weight
- 1646.85 g/mol
- PubChem CID
- 16197727
- Purity
- 99%+ (HPLC verified per lot)
- Form
- Lyophilised powder
- Storage
- Store dry, 2°C to 8°C
§ Melanocortin Research Context
- MC1R receptor pharmacology
- Alpha-MSH analogue structure-activity research
- Melanocortin receptor signalling
- Melanogenesis-related laboratory research
- Comparative melanocortin analogue research
§ Quality & Batch Testing
Each batch of Melanotan I is independently tested before it ships. Purity is verified by HPLC (High-Performance Liquid Chromatography) at ≥ 99.5%, and the current lot displayed on this product page (LOT TM-2466) corresponds to the certificate of analysis available under the Lab certificates accordion on this page.
Lot-specific COA documentation is published here before purchase and ships in the box. To confirm a lot after delivery, visit Verify your product.
§ Research References
- Afamelanotide / Melanotan I · PubChem CID 16197727PubChem (NCBI)
- Melanocortin-1 receptor (MC1R) pharmacology researchPubMed · Rees
- NDP-α-MSH structure-activity research (alpha-MSH analogues)PubMed · Sawyer et al.
§ FAQ
- What is Melanotan I?
- Melanotan I is a synthetic linear alpha-MSH analogue investigated in melanocortin-receptor research. It is commonly identified in chemical databases as afamelanotide / NDP-alpha-MSH.
- Is Melanotan I also called Melanotan 1?
- Yes. Melanotan I and Melanotan 1 refer to the same chemical identity, the Roman-numeral and Arabic-number spellings are interchangeable.
- What is another name for Melanotan I?
- Chemical databases and research literature commonly identify the same peptide as afamelanotide or NDP-alpha-MSH.
- Is Melanotan I the same as Melanotan II?
- No. Melanotan I is a linear alpha-MSH analogue; Melanotan II is a distinct cyclic peptide with a different structure and different receptor profile. Findings for one should not automatically be assigned to the other.
- What receptors are studied in Melanotan I research?
- Published research primarily examines activity at the melanocortin-1 receptor (MC1R) alongside the wider melanocortin-receptor family in structure-activity work.
- Is PepDirect Melanotan I intended for human use?
- No. PepDirect supplies this material as a laboratory research product. It is not marketed as, or represented as, the licensed medicinal product.
- How is PepDirect Melanotan I tested?
- Every lot is supplied with lot-specific documentation. HPLC purity is reported on the product hero and full identity information is captured in the lot Certificate of Analysis.
- How is PepDirect Melanotan I tested?
- Melanotan I is tested by HPLC to a purity of ≥ 99.5%. The current lot displayed on this page is TM-2466. A lot-specific Certificate of Analysis is published on the product page before purchase and ships in the box.
- Is this intended for human use?
- No. All PepDirect products are sold strictly for laboratory and research use only, and are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
- How quickly does PepDirect ship?
- Orders placed before 3:00 PM GMT are dispatched the same business day. Orders placed after 3:00 PM GMT are dispatched the next business day, with tracked delivery in 1-2 business days across the UK and EU. Shipping is calculated and shown at checkout based on destination.
- Does PepDirect provide a Certificate of Analysis?
- Yes. Every lot's COA is published on the product page before it ships, and the same PDF is included in the box.
- What is your guarantee?
- Same-day replacement on damaged or lost shipments, or a full refund on request, no questions asked.
§ Intended Use
This product is intended strictly for laboratory research applications by qualified personnel. It is not approved for human or animal consumption, and must not be used in foods, drugs, supplements, cosmetics, or diagnostics.
§ Legal Disclaimer
This compound and the statements on this page have not been evaluated by any regulatory body. No claims are made regarding diagnosis, treatment, mitigation, or prevention of any disease. Use is restricted to qualified researchers operating in appropriate laboratory environments.
§ Terms of Sale
By purchasing this product, the buyer confirms they are a qualified researcher or institutional purchaser, and accepts full responsibility for its handling, storage, and lawful use.
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Laboratory preparation supplies
Raw vial research material requires appropriate laboratory preparation equipment. The available kit groups compatible preparation and handling supplies in one bundle.
- Bacteriostatic Water 10mL
- Mixing Syringe + Needle 3mL, 23G · 10-pack
- Insulin Syringes 30G × 8mm 1mL · 10-pack
- Alcohol Prep Wipes 100-pack

§ Often bought together
Pair it with.

Accessories
Mixing Needle — 23G
23G reconstitution needle — for drawing BAC water through the vial stopper.
- IN STOCK
- COA VERIFIED

Accessories
Insulin Syringes — 30G x 8mm · 1mL
30G × 8mm insulin syringes, 1mL barrel — for Raw Vial reconstitution & injection.
- IN STOCK
- COA VERIFIED

Accessories
Alcohol Prep Wipes — 70% Isopropyl
Individually wrapped 70% isopropyl alcohol pads — 100 per pack.
- IN STOCK
- COA VERIFIED

Accessories
Sharps Disposal Bin — 0.2L
Puncture-resistant container for safe disposal of used needles and syringes.
- IN STOCK
- COA VERIFIED
